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Search Term: " ellagic acid "
Compounds in pomegranate juice found to trigger cancer cell death   
Date:
February 09, 2019 10:05 AM
Cancer can be slowed down or perhaps even prevented with a proper diet containing anti-oxidants and anti-inflammatory agents. Now research has shown that pomegranate juice is a strong anti-cancer agent. It contains strong chemical compounds that heal, like ellagic acid and luteolin which combine to prevent the growth of cancer cells, in particular in regards to prostate cancer. Pomegranate juice is beneficial in other ways too because it is rich in vitamins, antioxidants, helps aid digestion, supports and promotes heart health. Key Takeaways:
"According to research, pomegranate juice and pomegranate extract contain powerful healing chemical compounds such as luteolin and ellagic acid that effectively work together to help prevent cancer cell growth, particularly prostate cancer cells." Read more: https://www.healthnutnews.com/compounds-in-pomegranate-juice-found-to-trigger-cancer-cell-death/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6014) Plants That Fight Against Cancer 
Date:
May 16, 2013 12:49 PM
As medical research continues to understand cancer and formulate ways to treat it, there has been a lot discovered about cancer fighting plants. There are chemicals in certain plants that have been shown to help prevent cancer, but there have also been plants that can fight cancer once it begins to develop. There are many plants that are considered to be herbs and are not a part of a typical person's everyday diet. However, many fruits and vegetables have been shown to be effective and are found at most super markets. Cruciferae Family
Good examples of these types of vegetables are those from the cruciferae family. Among vegetables in this family are broccoli, cabbage, kale, collard greens and cauliflower. The specific chemical that is helpful in fighting cancer is Indole-3-carbinol. Although this compound can be found in other plants, it exists in greater concentrations in this family of vegetables. Indole-3-carbinol works to inhibit and reduce the size of tumors. Although research is still ongoing, there has been significant work done on animals such as mice and rats that have demonstrated the effectiveness of Indole-3-carbinol. At the time of this writing, the data for its effect on humans is still inclusive, but the research is producing optimism in the medical community. It is in the area of prostate and breast cancer that have shown the best results, but there seems to have an effect on other forms of cancer as well. Another example of a natural chemical to help fight cancer is ellagic acid. This anti-oxidant is found in fruits and vegetables, but it is more prevalent in fruits. Various berries such as blackberries, raspberries and cranberries have the highest concentrations. Pomegranates have been found to have a very high concentration of ellagic acid as well. This chemical is just now beginning to be understood in how it fights cancer. Although research is in an early stage, it appears that ellagic acid acts to prevent the proliferation of carcinogens that cause cancer by stopping them from binding with human DNA. Even with research still being done and the results, in some cases, still unclear, nutrition has been shown to help prevent and fight cancer. If you begin to add certain vegetables and fruits to your diet, it will be beneficial to your overall health, and this will reduce your chances of getting many forms of cancer. Other than an allergy to a certain plant, there are no side effects when eating several servings of fruit and vegetables every day of your life. No one has every suffered an ill effect from adding broccoli to their diet. The best way to take advantage of cancer fighting plants is to consume a variety of them throughout the day. Unless there is a particular type of fruit or vegetable that you love, it is best to mix up the types you eat so that you do not get tired of the food. You should also eat fruits and vegetables as fresh as possible. Although cooked vegetables still have nutritional value, they lose much of their nutritional content when heated. A well balanced diet with very little red meat can go a long way against the fight with cancer. If you can not consume enough raw vegetables on a daily basis, give these vegetable food concentrates in supplement form a try:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2837) Very Berry - Antioxidants
Date:
December 01, 2008 10:23 AM
It has been suggested that eating berries may be a delicious and great way for a person to protect themselves against heart disease. Blueberries are full of antioxidants, called anthocyanins, which have been shown to keep the memory sharp as you age. Raspberries, on the other hand, contain ellagic acid, which is a compound containing anti-cancer properties. All berries are a great source of fiber for the body, a nutrient that is extremely important for a healthy digestive system. More so, berries have recently been studied for their effects on heart health. A recent study published by the American Journal of Clinical Nutrition found that people who ate berries on a daily basis had higher levels of HDL cholesterol, which is healthy for the heart, lower blood pressure, and less blood platelet clumping, which is a factor that can help to protect people against dangerous blood clots. A new study, which tested seventy-two people who had one or more risk factors for heart disease, tested for the effects of eating berries on markers that deal with cardiovascular health. This trial, which lasted eight weeks, had half of the people eating berry mixtures of bilberries, lingon berries, black currants, strawberries, and raspberry and chokeberry juices two times each day. A combination of different berries was used in order to ensure that a large amount of polyphenols were taken in. As a control, the other people were given sugar water, sweetened wheat or rice cereals, or marmalade. Among those people who had the highest initial blood pressure, systolic blood pressure dropped 7.3 mm Hg in the berry group compared to only 0.2 mm Hg in the control group. Although total cholesterol levels were unchanged, those people who were a part of the berry group had a 5.2 percent increase in protective HDL cholesterol levels. Eating berries also stopped platelet function, which means that it takes longer for blood platelets to clump together and begin forming clots. Berries are good for you because they contain many beneficial substances such as polyphenols, potassium, vitamin C, folic acid, and fiber. Polyphenols are also found in cocoa, tea, red wine, onions, and other fruits and have attracted a lot of attention recently because of their potential health benefits. Some recent reports have concluded that polyphenols may potentially help to protect against both heart disease and cancer. Although the way that polyphenols work to promote health is not completely understood, it is assumed that it is tied to their antioxidant properties and their ability to enhance the body’s immunity while repairing DNA damage that occurs from smoking and exposure to other toxins. The findings of these studies are extremely significant because they may be partly responsible for explaining the role it holds in protecting the cardiovascular system. By eating fruits and vegetables a person increases the efficiency and health of their cardiovascular system significantly. Other types of studies have recently been warranted so that they may identify the compounds and mechanisms that are responsible for the effects that have been observed to this date. Berry supplements are also available at your local or internet health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1943) Fruit and Vegetable Lightning drink mixes from Natures Plus
Date:
February 06, 2007 02:41 PM
Enjoy the Rainbow – the Color Wheel of Fruits and Vegetables
We’ve all heard the statistics, and have probably seen the signs in the produce section of our favorite grocery store: eating 5 servings of fruits and veggies a day is important,
Chances are also pretty good that we’ve also seen the newest food pyramid, encouraging Americans to “eat a rainbow of frits and vegetables.” That is, choose from the rich variety of colors for the best all-around health benefits.
In this Ask the Doctor, we’re going to look at the unique health components of different colored fruits and vegetables, and why they’re so important. Plus, we’ll learn about supplemental options, like fruit and vegetable drink mixes, for those days when our diets just aren’t that great.
Q. What’s the big deal about fruits and vegetables?
A. Well, for the main reason that they are whole foods – created by nature (or at least generations of farming) and are rich in a variety of nutrients. Processed foods can’t match the health benefits of strawberries or broccoli – items that have fiber, vitamins, and enzymes built right in.
Q. What does “eating a rainbow” of fruits and vegetables really mean?
A. This is simply an easy way of remembering to get as much color variety in your diet as possible to maximize your intake of a broad range of nutrients. The colors of fruits and vegetables are often a tangible clue to the unique vitamins and other healthy substances they contain. Getting a variety of colors, therefore, means getting a variety of the essential nutrients your body needs to stay healthy and strong.
Enjoying the Rainbow: Fruit and Vegetable Benefits:
Q. Can you tell me a little more about the healthy components of fruits and vegetables?
Let’s take a look at some of the most well-studied and important nutrients:
Quercetin is found in apples, onions and citrus fruits (also is hawthorn and other berries and apple-related fruits usually used in traditional herbal remedies and modern supplements). It prevents LSL cholesterol oxidation and helps the body cope with allergens and other lung and breathing problems.
Clinical studies show that quercetin’s main points of absorption in the body appear to be in the small intestine – about 50%. The rest – at least 47% is metabolized by the colonic micro flora – the beneficial bacteria such as Lactobacillus acidophilus and Bifidobacterium longum. You may consider adding these beneficial bacteria (found in yogurt) either through the diet or a supplemental form.
ellagic acid is a component of ellagitannins – dietary polyphenols with antioxidant (and possibly anticancer) properties. Polyphenols are the basic building blocks of many plant-based antioxidants. More complex phenolic compounds, such as flavonoids are created from these molecules.
ellagic acid is found in many fruits and foods, namely raspberries, strawberries, pomegranates, and walnuts. Clinical studies suggest that ellagitannins and ellagic acid act as antioxidants and anticarcinogens in the gastrointestinal tract.
Ellagitannins are durable antioxidants, and happily, they do not appear to be diminished by processing, like freezing. This means the benefits are still strong, even in frozen packs of raspberries or strawberries, or some of the better multi-ingredient supplement drink mixes.
In scientific studies, ellagic acid also showed an anti-proliferative effect on cancer cells, decreasing their ATP (adenosine triphosphate) production. ATP is the molecule that provides the primary energy source for the cells in our bodies. In a sense, ellagic acid seems to deprive cancer cells of their fuel.
Beta-Carotene: Probably the best-known of the carotenoids, beta-carotene is converted by the body into vitamin A. Many vegetables, especially orange and yellow varieties, are rich in this nutrient. Think summer squash, yams and of course, carrots.
Beta-carotene has long been associated with better eyesight, but it has other benefits, too. In a scientific study, beta-carotene decreased cholesterol levels in the liver by 44% and reduces liver triglycerides by 40%.
Lycopene is a carotenoid mostly found in tomatoes, but also in smaller amounts in watermelon and other fruits. Clinical studies have shown that lycopene consumption may decrease the risk of prostate cancer. In fact, high intakes of lycopene are associated with a 30% to 40% reduced risk. And, as good as beta-carotene is, its cousin, lycopene, seems to be an even stronger nutrient, protecting not just against prostate cancer, but heart disease as well.
Lutein is found in many fruits and vegetables, including blueberries and members of the squash family. Lutein is important for healthy eyes, and in fact it is found in high concentrations naturally in the macular region of the retina – where we see fine detail. It is one of the only carotenoids, along with its close sibling zeaxanthin, that is found in the macula and lens of the eye.
Lutein also supports your heart, too. In a scientific study, lutein reduced atherosclerotic lesion size by 43%. In other words, high intakes of lutein may actually help prevent coronary artery disease!
Interestingly, as is the case with lycopene, cooking or processing foods with lutein may actually make it more easily absorbed.
In clinical studies, men with high intakes of lutein (and its close cousin, zeaxanthin, found in broccoli and spinach) had a 19% lower risk of cataract, and women had a 22% decreased risk, compared to those whose lutein intakes were much lower.
Vitamin C: One of the best-known nutrients out there, vitamin C keeps our immune system strong; speeds wound healing, and promote strong muscles and joints. A free-radical fighter, vitamin C prevents oxidative damage to tissues, builds strength in collagen and connective tissue, and even reduces joint pain.
Sources of vitamin C are scattered throughout the spectrum of fruits and vegetables.
Potassium: Most Americans are deficient in potassium. For the most part, it’s hard to get too much of this valuable mineral. Potassium does great things for our hearts. Higher intakes of dietary potassium from fruits and vegetables have been found in clinical research to lower blood pressure in only 4 weeks.
Many researchers believe that the typical American diet has led to a state of chronic, low-grade acidosis – too much acid in the body. Potassium helps change pH balance to a more alkaline environment in the body and increases bone density.
This was proven in the long-running Framingham Heart Study which showed that dietary potassium, (along with magnesium and fruit and vegetable intake) provided greater bone density in older individuals.
Fiber is another food component many just don’t get enough of – especially if they’re eating a “typical American diet.” Fruits, vegetables and whole grains are excellent sources of fiber. However, fiber from a good fruits and vegetable drink mix should be derived from inulin and chicory root. This soluble fiber source not only adds to the overall amount of fiber you need (25 to 38 grams a day), but also provides a nice “nesting ground” for the beneficial bacteria that populate the intestines. And, even though some fiber has a bad rap for inhibiting mineral absorption, inulin and chicory root are “bone building” fibers – they actually help the body absorb calcium.
Flavonoids are an overarching term that encompasses flavonols, anthocyanidins, and flavones, isoflavones, proanthocyanidins, Quercetin and more. They are almost everywhere: in fruits, vegetables, grains, herbs, nuts and seeds – even in the coffee, wine and tea we drink. Flavonoids are responsible for the colors in the skins of fruits and the leaves of trees and other plants.
Flavonoids have many health benefits. They can help stop the growth of tumor cells and are potent antioxidants. Additionally, flavonoids have also been studied for their ability to reduce inflammation.
Anthocyanins: High on the list of important “visible” nutrients are anthocyanins. They color fruits and vegetables blue and red.
Anthocyanins are members of this extended family of nutmeats, the flavonoids. Typically found in high amounts in berries, anthocyanins are readily absorbed in the stomach and small intestine.
As antioxidants, anthocyanins dive deep into cell membranes, protecting them from damage. IT may be one reason why the anthocyanins from blueberries are considered such an important component in battling neuronal decline, like Alzheimer’s. Blackberries, raspberries, and strawberries are also excellent sources of this flavonoids group.
SDG lignans, (short for secoisolariciresinol diglucoside) are polyphenolic components of flaxseed, pumpkin and other herbal sources. Much of the recent research surrounding lignans has focused on flaxseed. In scientific and clinical studies, lignans from flaxseed support hormonal balance and may have cancer-preventing abilities. In fact, in one study, flaxseed lignans reduced metastatic lung tumor by 82% compared to controls.
The lignans in pumpkin seed, also considered a major source, target 5-alpha reductase activity.
This enzyme catalyzes the conversion of testosterone into the more potent dihydrotestosterone (DHT). DHT, like testosterone, is a steroid hormone or androgen. Androgens are responsible for the development and maintenance of masculine sex characteristics in both men and women. Excess levels of DHT can cause serious problems with prostate or bladder health. That’s why modulation of the 5-alpha reductase enzyme is so important – it helps maintain healthy testosterone and DHT levels. By balancing the levels of these key hormones, pumpkin seed lignans provide protection for prostate and bladder cells.
In addition, pumpkin seed has been shown to modulate the enzyme aromatase. Aromatase is present in the estrogen-producing cells of the adrenal glands, ovaries, testicles, adipose tissue, and brain. Aromatase converts testosterone, an androgen, into estradiol, and estrogen.
Inhibition of the aromatase conversion can help maintain a balance of healthy testosterone levels in women, which has been shown to strengthen pelvic muscles and reduce incidence of incontinence.
In fact, a clinical study, involving a pumpkin extract in conjunction with soy, resulted in significant support for bladder health. After two weeks of supplementation, 23 of the 39 postmenopausal women enrolled in the study showed great improvement in urinary frequency and sleep. By the end of the six week study, 74.4 percent of participants found pumpkin extract safely and significantly improved “nocturnia,” that is, the need to urinate frequently at night. For individuals with 2 to 4 episodes of nocturnia prior to the stud, and 81.8% improvement was seen – also showing great improvement in sleep quality. After all, if you don’t have to wake up every couple of hours to go to the bathroom you’re bound to get better sleep.
Beta glucan: Mushrooms are intense immune-boosting powerhouses due to their beta-glucan content. Three well-studied power-house mushrooms that contribute beta glucan to the diet include maitake, reishi and shiitake.
The most significant constituents of mushrooms are long chain polysaccharides (molecules formed from many sugar units) known as beta-glucan. These huge molecules act as immunoregualtors in the human body, helping to stabilize and balance the immune system.
This includes specific support of white blood cells, or lymphocytes, the primary cells of the immune system. Lymphocytes fall broadly into three categories: T cells, B cells, and natural killer (NK) cells.
In one clinical study, 165 patients with various types of advanced cancer were given maitake mushroom compounds alone or with chemotherapy. Cancer regression or significant symptom improvement was observed in 58% of liver cancer patients, and 62% of lung cancer patients. Plus, when maitake was taken in addition to chemotherapy, the immune cell activities were enhanced 1.2 to 1.4 times, compared with chemotherapy alone.
In another clinical study, researchers determined that Reishi increased the number of cancer killing white blood cells and made them more deadly to cancer cells.
And, in a scientific study of human breast cancer and myeloma cancer and myeloma cancer cell lines, shiitake compounds provided a 51% antiproliferative effect on the cells – inducing “apoptosis’ – the programmed cell death that should occur naturally.
While beta-glucan are distributed throughout the mushroom body, the beta-glucan concentrations are significantly higher in the mycelium – the interwoven fibers or filaments that make up the “feeding structure” of the mushroom.
Bioflavonoids are commonly found in bright yellow citrus fruits, including lemons, limes and oranges. They are responsible for the bright pigment found in the skin of the fruit, and are considered a “companion” to vitamin C, seeming to extend the value of the nutrient within the body.
Hesperidin is just one of the valuable bioflavonoids found in citrus. Hesperidin appears to lower cholesterol levels, as well as support joint collagen in examples of rheumatoid arthritis.
Epigallocatechin gallate (EGCG):
Polyphenols, most notably EGCG, or epigallocatechin gallate, are well-studied and powerful components of tea. EGCG has been shown to reduce colon and breast cancer risk. Green tea also boosts the immune system and encourages T-cell formation – part of the front-line defense of our bodies against sickness and disease.
Q. I’ve been seeing articles about fruits, vegetables and supplements touting “high ORAC value.” What does this mean?
ORAC is an acronym for Oxygen Radical Absorption Capacity, and is simply a measurement of antioxidant activity of nutrients. Oxygen radicals, or free radicals, are unstable molecules. They grab electrons from other cells to use for themselves, and in the process can damage them. It is believed that free radical activity plays a role in the development of many diseases such as heart disease and cancer, and also plays a role in aging.
Antioxidants help prevent this damage by “loaning out” extra electrons to stabilize free radicals/ Consider any fruit or vegetable with a high ORAC rating as having a lot of “antioxidant power.”
I know I should eat more fruits and vegetables, but it just seems so hard to get five servings a day.
The number one excuse I hear for not buying frits and veggies is that “fruits and vegetables are too expensive.” But are they really? Certainly, fresh foods that aren’t in season and have to be shipped a distance can be a bit pricey. If anyone added up how much spend on fast food, or prepackaged or processed snacks, it would probably be shocking.
Luckily, there are many ways to get your “Daily 5”. For instance, frozen fruits and veggies retain much of their nutrient profile. They can be an excellent alternative when certain foods are out of season. So too, are fruit and vegetable drink mixes – excellent supplemental sources of some of the nutrients our bodies need most.
More recently, the American
Of course, for people not accustomed to the fiber in fruits and veggies, there is some reason to think it’ll increase gas. When cell walls break down, and fiber passes through the system, it can create flatulence. Folks who eat fruits and vegetables every day generally don’t have this problem. Their systems are already accustomed to it.
For those just starting out on a better diet, however, start slowly – it helps your body adapt. Cooking vegetables can help, too, because it begins breaking down the cell walls early on.
One thing is certain, however. The “Typical American Diet” and good health are mutually exclusive. The increase in type 2 diabetes, heart disease, high cholesterol, and hypertension all point to the abuse our bodies suffer by eating diets high in fatty meats, processed sugars, and refined grains.
Q. Can I just drink fruit and vegetables drinks in place of 5 servings of fruits and vegetables?
Green drinks and fruit and vegetable drink mixes aren’t meant to replace whole foods, but they can be an excellent substitute when you’re rushed or traveling or just trying to fill everyday nutritional gaps. Their whole food ingredients absorb very easily and gently in the gut, and many of these drink mixes contain healthy doses of fiber, too.
Green drink mixes and food-based drink mixes combine many colorful fruits and vegetables and sometimes grasses in a healthy, mixable supplement assortment. While there have been many advancements in the field of green drinks, there are only a few that take the primary reason we eat into consideration: taste!
Happily, there are some companies out there with great-tasting drink mixes that also formulate based on the color concept, ensuring you get the broadest assortment of nutrients from a full range of fruit and vegetable colors to promote optimal health.
High-quality fruit and vegetable drink mixes offer the best from nature’s color wheel in a convenient and great-tasting supplement. So, the next tie you feel like taking a coffee break – try a fruit and veggie break instead. Your body and spirit will thank you.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1451) Mangoni - Complete SuperFruit Food 1oz equals 3 servings of Vegetables
Date:
December 27, 2006 12:26 PM
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1440) Pomeratrol™ Fact Sheet
Date:
December 19, 2005 09:09 AM
Pomeratrol™ Fact SheetNeil E. Levin, CCN, DANLA 9/28/04USER: Those needing antioxidant protection; People with a family history of cell growth abnormalities; Anyone concerned with aging KEY INGREDIENT(S): Pomegranate fruit standardized extract 200 mg. (Punica granatum) containing 80% total polyphenols, including 40% ellagic acid, Resveratrol (100% trans-resveratrol) 20 mg. from a blend of Japanese knotweed root extract (Polygonum cuspidatum) and grape skin extract (Vitis vinifera) POTENTIAL BENEFITS: ellagic acid is a polyphenol compound found in raspberries, strawberries, pomegranates, and other fruit. It has been shown to normalize cell death of abnormal cells, a process called apoptosis. This enhances the body’s cell growth control system by providing an important plant substance. It may bind to DNA to prevent damage to this all-important genetic material. This is a key step in preventing cell damage that leads to signs of aging. The American Cancer Society says that research in animal and laboratory models has found that ellagic acid inhibits the abnormal growth of certain cells. Research at Ohio State University indicates that berries typically contain a few milligrams per ounce of ellagic acid, the actual level varying quite a bit from variables such as species, variety and growing conditions. Resveratrol is an antioxidant compound that is a phytoestrogen, or plant estrogen, which is protective of hormone-mediated cells in the body. Resveratrol is a potent antioxidant if stabilized. If not stable, it may quickly metabolize out of the body. This compound is believed responsible for some of the beneficial effects of moderate red wine drinking on the cardiovascular system. Resveratrol is also considered to be beneficial to smokers’ lung tissue if it is stabilized to last long enough in the system to be transported there. Resveratrol is also an inhibitor of the COX-2 inflammatory enzyme and encourages cell death (apoptosis) of abnormally growing cells. In insect experiments resveratrol even repaired DNA, leading to a longer life for healthy cells even as it helped get rid of unhealthy cells. Again, this ability to protect cells and help the body rid itself of abnormal cells is a key factor in preventing signs of aging. One liter of red wine contains between 1.5 and 3 mg. of resveratrol. OTHER IMPORTANT ISSUES: Resveratrol is a difficult substance to stabilize. Because of the difference between resveratrol produced in the oxygen-poor environment in red wine and the form of resveratrol in unstabilized supplements, it has long been thought that resveratrol supplements were not very effective in comparison with wine. Knowing the importance of how a resveratrol supplement is metabolized, Now’s scientific staff has recently developed a special technique of stabilizing this compound in order to have an antioxidant effect closer to drinking a good glass of wine. While both trans and cis forms of resveratrol are naturally occurring, most of the recorded health benefits are attributed to the trans form. Now’s Pomeratrol provides trans-resveratrol. DOSE: One capsule per day. Resveratrol has been used safely in studies at doses equivalent to 500 mg./day. COMPLEMENTARY PRODUCTS: Other antioxidants and plant compounds: Vitamin C, pycnogenol, grape seed extract, and alpha lipoic acid.
CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. There are some indications that resveratrol is a mild anticoagulant ("blood thinner"), and it also may help keep blood vessels to remain open and flexible. Caution should be used by those on blood-thinning drugs. Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1039) POMERATROL
Date:
December 19, 2005 09:06 AM
POMERATROLPomeratrol™ - NOW® Pomeratrol™ gets its anti-aging properties from two cell protecting agents, pomegranate and trans-Resveratrol. Fueled by powerful antioxidant compounds that include polyphenols (standardized to 80%) and anthocyanidins, pomegranate is also high in ellagic acid (standardized to 40%) that helps support healthy cellular function. In addition, the trans- Resveratrol in Pomeratrol™ is a hard-working antioxidant that helps sustain healthy cell cycles while protecting against DNA damage. This combination encourages normal cellular growth and renewal – a key factor in healthy aging.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1038) The Free Radical Theory
Date:
December 14, 2005 12:11 PM
The popular theory has been the subject of a great deal of research. Developed by Denham Harman, M.D., Ph.D., at the University of Nebraska in 1956, the free radical theory proposes that unstable molecules known as free radicals are responsible for inflicting extensive cellular damage, which causes cell death and dysfunction and eventually, disease. The most common type of free radicals are oxygen derived, and free radical damage is often referred to as oxidation. Environmental sources of free radicals include radiation (I.E., sun exposure, X-rays), ozone and nitrous oxide, heavy metals (i.e., mercury, cadmium, lead), smoke, alcohol, saturated fat, and other chemicals and pollutants. The body itself generates free radicals in performing essential bodily functions including energy production and immune activities. Fortunately, the body also has the ability to create antioxidants to neutralize the free radicals and prevent extensive cellular damage. When free radicals are not neutralized by antioxidants, they inflict large-scale cellular damage which can cascade and lead to age-related degenerative diseases such as osteoarthritis, osteoporosis and age –relaged macular degeneration. For example, free radical damage to joint cells may cause the cartilage to become rough or break down, and can lead to the development of osteoarthritis. Antioxidants are needed to comb at free radicals and prevent this cellular damage. “Oxidative stress can lead to DNA mutations, cell death, and disease, all of which contribute to aging,” said Gerald R. Cysewski, president and chief executive officer (CEO) at Cyanotech corp. “Antioxidants are produced naturally by the body to combat oxidative stress by neutralizing free radicals. Increasing the amount of antioxidants in one’s system by consumption of supplements can provide further protection from the damaging effects of free radicals.” Because the body is continually assaulted by free radicals, antioxidant supplementation is often necessary. “by taking certain nutrients that our bodies stop producing over time, supplements help us to maintain a youthful look and health, which in turn enhances the quality of life,” Alkayali said. “Furthermore, supplements can help decrease oxidative stress that may otherwise accompany age-related illness and disease.” Many Substances are known antioxidants including certain enzymes, vitamins, phytochemicals and minerals, and include Vitamin C, Vitamin E, alpha-lipoic acid, coenzyme Q10 (CoQ10), Carotenoids, Selenium, superoxide dismutase, melatonin, quercetin, catechins, and zinc. Consuming a diet high in plant sources of powerful antioxidants is an important step to deter ageing, because nutrients from foods are often highly bioavailable and can act synergistically to increase their health benefits. Garlic contains several antioxidant phytochemicals and minerals including allicin, beta-carotene, quercetin, selenium and zinc, and may have a protective effect against stomach and colorectal cancers. Catechins are potent antioxidants flavonoids, with the best known source being green tea; they include gallocatechin (GC), epigallocatechin (EGC), epicatechin (EC) and epigallocatechin gallate (EGCG). These antioxidants are being studied for their powerful abilities to combat free radical damage. In particular, EGCG has been researched for its reported protection against certain cancers and Alzheimer’s disease. Green Foods such as seaweed, sea vegetables, young grain grasses and shoots, broccoli, cabbage and other green leafy vegetables pack a nutritional punch due to their concentratged amounts of antioxidant carotenoids, vitamins and the enzyme superoxide dismutase (SOD). SOD is produced by the body and neutralizes free radicals known as superoxide radicals, which cause damaging fat oxidation. GliSODin is a patented form of SOD derived from cantaloupe and bound to a wheat protein for superior bioavailability. “GliSODin promotes the body’s production of its own endogenous antioxidants, including SOD, catalase and glutathione peroxidase, in virtually every cell,” said Eric Anderson, brand manager at P.L. Thomas. “This activation of the cellular antioxidant defenses across the whole body creates a state of alertness against any shock of oxidative stress, including sun rays, to which our body may be exposed.” Pomegranates contain two powerful antioxidants—ellagic acid, derived from fruit’s seeds, and punicaligans, found in the juice. “Research has shown that the juice from the pomegranate, rich in polyphenols, reduces oxidative stress by helping to produce enzymes to fight free radicals,” Alkayali said. NeoCell Corp. manufactures of ellagic-acid based Pomegranate Power, while P.L. Thomas supplies POM40p, a kosher-free pomegranate juice extract standardized to 40-precent punicocides, polyphenols belong to the punicalagin family. Consumer demand is on the rise for products that address degenerative health conditions, including supplements that support function of the bones, joints, eyes. According to a June 2005 report by the freedonia group, “Bone and joint care products will continue to dominate the health maintenance segment, spurred by a growing customer base and a plethora of new and improved products expected to soon enter the marketplace.” The report also projected rapid gains for vision care. “Demand for vision care products will be propelled by aging baby boomers who are becoming aware of debilitating eye conditions and seeking both preventive measures and ameliorative treatments.” Dietary Supplements can help prevent and ease symptoms of age-related diseases affecting the joints, bones and eyes, including osteoarthritis, osteoporosis and age-related macular degeneration (AMD).
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1013) Vitaberry Plus + Super Fruit Antioxidant
Date:
December 07, 2005 05:43 PM
Vitaberry Plus +™ Super Fruit AntioxidantBy Nilesh Patel, NOW Quality Assurance, April 20, 2005 Why are FRUITS AND VEGETABLES important? “Diets rich in FRUITS AND VEGETABLES may reduce the risk of some types of cancer and other chronic diseases.”- National Cancer Institute. OXYGEN AND ANTIOXIDANTS As we all know, “Oxygen is critical to life,” but is itself a double-edged sword. While oxygen is necessary to sustain life and for natural defense against microbes, too much oxygen in our cells can lead to the production of “free radicals” (mitochondrial respiratory chain) or ROS (Reactive Oxygen Species). Free radicals come in many forms - singlet oxygen, hydrogen peroxide, superoxideperoxynitrite, to name a few - but all have one commonality. Each has an unpaired (unbalanced) electron, a situation it remedies by stealing an electron from a stable molecule. This sets off a domino effect of oxidation, a chain reaction that usually ends up damaging cellular integrity and compromising overall health. Nature has a defense system in place to protect these processes in the form of antioxidants. Whether endogenous (produced by the body, such as liver enzymes, SOD, coenzymes and sulfur-containing compounds) or exogenous (obtained through the diet, such as vitamins C & E, bioflavonoids, carotenes, etc.), antioxidants “quench” free radicals by donating an electron to stabilize a molecule, thus controling the chain reaction and stopping the oxidation “domino effect”. ANTIOXIDANT-RICH FOODS Research suggests that eating plenty of foods high in antioxidants helps to slow the processes associated with aging and protect against many chronic diseases. Maximizing one’s antioxidant power will enhance overall health. Fruit and vegetables contain both nutritive and non-nutritive factors that can affect oxidative damage and enzymatic defense and might contribute to redox (antioxidant and prooxidant) actions. A new “6-a-day” study looked into the effects of fruits and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers by The Danish Institute for Food and Veterinary Research in Denmark. The study found that fruits and vegetables increase erythrocyte glutathione peroxidase activity and resistance of plasma lipoproteins to oxidation more efficiently than do the nutritive factors (vitamins and minerals) that the fruits and vegetables are also known to contain. Certain berries, such as blackberries, also contain salicylates, which are also linked to heart health and prevention of atherosclerosis. The protective effects of fruits and vegetables intake on both heart disease death and deaths in general have previously been demonstrated but researchers at the Human Nutrition Research Center on Aging at Tufts University, Boston. Quercetin is an anti-oxidizing flavonoid found in many berries (such as cranberries, bilberries, blueberries, strawberries, etc.) and can prevent CVDs (coronary vascular diseases), according to a recent Finnish study. All these natural plant polyphenols are responsible for the colors of many red and purple berries, fruits, vegetables and flowers. GOVERNMENT GUIDELINES The new federal guidelines released earlier this year by the U.S. Department of Health and Human Services (HHS) and U.S. Department of Agriculture (USDA) recommend eating more fruits and vegetables, combined, than any other food group -- five cups or about 10 servings a day for most adults. The amount of fruits and vegetables recommended has increased for men and women of every age. “Fruits and vegetables are the "good news" story of the new Dietary Guidelines for Americans for food-loving consumers, the industry and America's public health”, stated the Produce for Better Health Foundation (PBH). Eating a variety of colorful phytochemical-rich fruits and vegetables has been associated with lower risk of some chronic diseases such as cancer and heart disease. Many authoritative organizations such as the National Cancer Institute and The American Heart Association recommend getting phytochemicals from whole foods, such as fruits and vegetables, rather than from individual component supplements. The Scottish government is promoting healthy eating through a scheme designed to increase purchasing of fruit and nutritional foods. Scottish health minister Andy Kerr said, "This initiative shows that healthy eating can be good for customers and good for business." Scottish women are said to have the highest rates of death from lung cancer in the world as well as the highest rates in Europe for coronary heart disease. They also have low consumption of fruits and vegetables, shown in studies to help protect against some cancers and benefit heart health. ROS (Reactive Oxygen Species) Free radicals and oxygen free radicals play an important role in the development and progression of many brain disorders such as brain injury, neurodegenerative disease, and Down syndrome. Oxidative stress is an important factor in the etiology and pathogenesis of diabetes & is also linked to other host of degenerative health conditions. Fortunately, antioxidants are available to support the body’s defense and fight disease and aging. Examples of “Fast acting antioxidants” in the body (serum) are: uric acid (polyphenols), ascorbate, bilirubin, vitamin E (the later two are lipid soluble). Examples of “Slow acting antioxidants” are glucose, urea nitrogen etc. In short, free radicals, reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated as by-products of normal cellular metabolism. Their deleterious effects are minimized in vivo (in the body) by the presence of antioxidant systems. How do Antioxidants work? Antioxidants are substances in plants that help maintain health. Antioxidants protect against damage to cells caused by too many “free oxygen radicals,” which form because of the effects of oxidation. Smoking, sunlight, heavy exercise, and pollution all increase oxidation in the body. Most people would benefit by eating more (five to nine or more servings) fruits and vegetables & colorful plant foods, such as purple, dark green, yellow, orange, blue, and red ones, each day. These have healthful pigments along with antioxidant nutrients such as vitamin C, carotenoids, beta-carotene, lycopene, lutein, zeaxanthin, vitamin E, selenium, flavonoids, and other beneficial substances. There are numerous ways in which these antioxidants affect, but can be explained in two groups: Alpha (a) Effects: This refers to the scavenging or neutralizing of free radicals. These effects do not change the way humans (or animals) feel. There are also no noticeable health, psychological or emotional benefits. While there are no obvious changes, increased total antioxidant intakes are associated with decreased tumor rates, prevention of heart attacks and increased longevity. Beta (ß) Effects: These are the changes on health, psychological or emotional state that you or others will notice. In this case, the antioxidant is affecting metabolic processes (enzymes) with consequent changes in the physical (improvement in joint movements, improved skin condition, tissue damage recovery), emotional (better ability to cope with stress) or psychological state (increased alertness). The ORAC value Because most of the active nutritional components in fruits and vegetables are antioxidants, accurate measurement of antioxidant activity serves as a good indicator of potential health benefit. Scientific opinion runs high that ORAC (Oxygen Radical Absorption Capacity) will eventually become a government standard of reference for overall daily fruits and vegetables intake. ORAC units are a measurement of the ability of food to stop oxidation. It is most generally expressed in terms of Trolox equivalent per gram (µmole Trolox equivalents (TE)/g). POPULATION DATA A survey done by the National Research Council indicates that only 10% of the US population consumes the recommended five servings of fruits and vegetables per day. The equivalent to eating 5 mixed servings of fruits and vegetables per day is about 1,670 ORAC units. Based on scientific evidence it is suggested that daily antioxidant intake should be increased to between 3,000 and 5,000 ORAC units per day, per human subject, in order to reach a significant antioxidant capacity in blood plasma and other tissues. WHAT IS NOW DOING TO HELP? In accord with our mission, “To provide value in products and services that empower people to lead healthier lives,” NOW® Foods is introducing an ALL-FRUIT-DERIVED antioxidant product called VitaBerry Plus +™ Super Fruit Antioxidant Vcaps (vegetarian capsules) (product number #3336). At time of manufacture this product provides an ORAC value of at least 2,500 units per serving from a full-spectrum antioxidant blend of fruits containing phytochemicals and phenolic compounds such as anthocyanins, proanthocyanins, chlorogenic acid, ellagic acid, quinic acid, resveratrol , many organic acids, resveratrol and vitamin C. VitaBerry Plus +™ is formulated with VitaBerry™ Hi-ORAC Fruit Blend [a proprietary blend of fruit extracts & concentrated powders containing Wild Blueberry (Vaccinium angustifolium) extract, Grape (Vitis vinifera) & Grape seed extract, Raspberry (Rubus idaeus) & Raspberry seed extract, Cranberry (Vaccinium macrocarpon), Prune (Prunus domestica), Tart Cherry (Prunus cerasus), Wild Bilberry (Vaccinium myrtillus) extract & Strawberry (Fragaria virginia)], Hi-Active™ Orange (Citrus sinensis) and Pomegranate (Punica granatum) min. 40% ellagic acid fruit extract. One gram of VitaBerry™ Hi-ORAC Fruit Blend provides at least 6,000 ORAC units (i.e., µmole Trolox equivalents (TE)/g). (Also watch for an upcoming antioxidant product from NOW called Enzogenol® (Pinus radiata bark extract from New Zealand) with Rutin (a flavonoid from South American fruit of Dimorphandra mollis) and Grapeseed extract. IS IT EFFECTIVE? Total ORAC value includes both lipophilic and hydrophilic components. VitaBerry Plus +™ contains only water/hydroethanol based extracts and concentrated (100:1 to 125:1) freeze-dried fresh fruit blends, so the lipophilic ORAC value is mere 2-4% of the total ORAC value. Glutathione peroxidase is a selenium-containing enzyme that decreases cell death from brain injuries. It also acts as a critical first-line antioxidant defense on the airway (respiratory) epithelial surface against ROS and RNS (reactive nitrogen species. Genetics research has found that the glutathione S-transferase gene controls the onset of Alzheimer’s, Parkinson’s disease etc. Taking glutathione (GSH) itself as a supplement does not boost cellular glutathione levels, since it breaks down in the digestive tract before it reaches the cells. So glutathione precursor dietary supplements (such as NAC and GliSODin), along with fruits and vegetables, are effective in boosting intracellular levels of GSH. The lungs have a defense system against the ROS oxidants consisting of low molecular weight antioxidants such as GSH and intracellular enzymes such as SOD, catalase and glutathione peroxidase to protect against the toxic effects of oxidants generated within the cells. Some of the primary effects of VitaBerry Plus +™ against the common reactive free-radical species or ROS are as follows: - Superoxide dismutase-SOD (destroys Superoxide radicals),- Catalase (neutralizes peroxides), - Functions similar to reduced Glutathione (GSH), - Glutathione peroxidase enzyme (detoxifies peroxides, using GSH as a reducing agent), - Functions similar to Glutathione S-transferase (GST), - Nullifies Superoxide-generating NADH/NADPH oxidase system In conclusion More concentrated than fresh berries, with over 6000 ORAC units per gram, VitaBerry Plus +™ provides consumers with the antioxidant power of almost 15 servings per day of FRUITS AND VEGETABLES ina convenient vegetarian capsule form! VitaBerry™ PLUS +™ (# 3336) provides a powerful, convenient way to supplement diets that do not include sufficient fruit and vegetable antioxidants Selected References: USDA/HHS guidelines report at: etaryguidelines/dga2005/document/
ls.com/proprietary/pdf/VitaberryBrochure.pdf g Kaplan M., Hayek T. , Raz A., Coleman R. and Aviram M. Pomegranate juice supplementation to apolipoprotein E deficient mice with extensive atherosclerosis reduces macrophages lipid peroxidation, cellular cholesterol accumulation and development of atherosclerosis. J. Nutr. 131: 2082-2089 (2001) Lars O Dragsted et. al., The 6-a-day study:effects if fruit and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers. American Journal of Clinical Nutrition, Vol. 79, No. 6, 1060-1072, June 2004 Fuhrman B. and Aviram M. Polyphenols and flavaonoids protects LDL against atherogenic modifications.In: Handbook of Antioxidants Biochemical, Nutritional and Clinical Aspects, 2nd Edition. Cadenas E & Packer L (Eds.) Marcel Dekker, NY(Pub.). 16:303-336 (2001) Wood, Jacqueline, et al. Antioxidant activity of procyanidin-containing plant extracts at different pHs. Food Chemistry 77 (2002) 155-161 Aviram M. Pomegranate juice as a major source for polyphenolic flavonoids and it is most potent antioxidant against LDL oxidation and atherosclerosis. Free Radical Research 36 (Supplement 1): 71-72 (2002) Jennifer Schraag, Antioxidants: Nature’s Way of Balancing Life. HSR Health Supplement Retailer, Vol. 11, No. 2, 24-27, February 2005 com/news/printNewsBis.asp?id=58665 com/news/printNewsBis.asp?id=58697
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=992) VitaBerry Plus+ Fact Sheet
Date:
December 07, 2005 05:38 PM
VitaBerry Plus+ Fact SheetNeil E. Levin, CCN, DANLA 3/18/05LIKELY USERS: Antioxidant users who want the best food source formula; People seeking polyphenols or ellagic acid supplements; Those who don’t eat fruit and want some of their benefits KEY INGREDIENTS: VitaBerry extract, Hi-Active Orange Extract, Pomegranate Extract (420 mg) (400 mg) (100 mg) MAIN PRODUCT FEATURES: This is a high antioxidant (high ORAC: 2,500 units per serving of oxygen radical absorbing capacity), proprietary blend of fruit extracts & concentrated powders containing Wild Blueberry extract, Grape & Grape seed extract, Raspberry & Raspberry seed extract, Cranberry, Prune, Tart Cherry, Wild Bilberry extract & Strawberry powder. Fortified with Hi-Active Orange Extract (Freeze-dried Orange (Citrus sinensis) powder with minimum of 40% vitamin C) and Pomegranate Extract (80% Polyphenols and 40% ellagic acid). Provides a broad-spectrum antioxidant blend with phytochemicals such as anthocyanins, chlorogenic acid, ellagic acid, quinic acid, resveratrol etc. in a single “0” size vegetarian capsule. There is a synergistic effect of mixing fruit antioxidants that provides antioxidant protection greater than is predicted by measuring each fruit source used in the mix individually. ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: There will be some natural variation in color, taste and odor from these fruit sources. A special freeze drying technique preserves the antioxidant value of whole fruits in a concentrated form. SERVING SIZE & HOW TO TAKE IT: Serving is 2 Vcaps. Take one or more servings per day as an antioxidant supplement. May be taken with food or on an empty stomach (this is food). COMPLEMENTARY PRODUCTS: All antioxidants. CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This information has not been reviewed by the FDA or the company posting it. Information given here may vary from what is given on the product label because this page represents my understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time. Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES: Bagchi D, Sen CK, Bagchi M, Atalay M. Anti-angiogenic, antioxidant, and anti-carcinogenic properties of a novel anthocyanin-rich berry extract formula. Biochemistry (Mosc). 2004 Jan;69(1):75-80, 1 p preceding 75. Review. PMID: 14972022 Gemma C, Mesches MH, Sepesi B, Choo K, Holmes DB, Bickford PC. Diets enriched in foods with high antioxidant activity reverse age-induced decreases in cerebellar beta-adrenergic function and increases in proinflammatory cytokines. J Neurosci. 2002 Jul 15;22(14):6114-20. PMID: 12122072 Huang D, Ou B, Prior RL. The Chemistry behind Antioxidant Capacity Assays. J Agric Food Chem. 2005 Mar 23;53(6):1841-1856. PMID: 15769103 Kay CD, Holub BJ. The effect of wild blueberry (Vaccinium angustifolium) consumption on postprandial serum antioxidant status in human subjects. Br J Nutr. 2002 Oct;88(4):389-98. PMID: 12323088 Mazza G, Kay CD, Cottrell T, Holub BJ. Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects. J Agric Food Chem. 2002 Dec 18;50(26):7731-7. PMID: 12475297 Prior RL, Cao G. Analysis of botanicals and dietary supplements for antioxidant capacity: a review. J AOAC Int. 2000 Jul-Aug;83(4):950-6. Review. PMID: 10995120 Prior RL, Cao G. In vivo total antioxidant capacity: comparison of different analytical methods. Free Radic Biol Med. 1999 Dec;27(11-12):1173-81. Review. PMID: 10641708 Prior RL, Hoang H, Gu L, Wu X, Bacchiocca M, Howard L, Hampsch-Woodill M, Huang D, Ou B, Jacob R. Assays for hydrophilic and lipophilic antioxidant capacity (oxygen radical absorbance capacity (ORAC(FL))) of plasma and other biological and food samples. J Agric Food Chem. 2003 May 21;51(11):3273-9. PMID: 12744654 Proteggente AR, Pannala AS, Paganga G, Van Buren L, Wagner E, Wiseman S, Van De Put F, Dacombe C, Rice-Evans CA. The antioxidant activity of regularly consumed fruit and vegetables reflects their phenolic and vitamin C composition. Free Radic Res. 2002 Feb;36(2):217-33. PMID: 11999391 Roy S, Khanna S, Alessio HM, Vider J, Bagchi D, Bagchi M, Sen CK. Anti-angiogenic property of edible berries. Free Radic Res. 2002 Sep;36(9):1023-31. PMID: 12448828 Sofic E, Rustembegovic A, Kroyer G, Cao G. Serum antioxidant capacity in neurological, psychiatric, renal diseases and cardiomyopathy. J Neural Transm. 2002 May;109(5-6):711-9. PMID: 12111462 Stintzing FC, Stintzing AS, Carle R, Frei B, Wrolstad RE. Color and antioxidant properties of cyanidin-based anthocyanin pigments. J Agric Food Chem. 2002 Oct 9;50(21):6172-81. PMID: 12358498
Wu X, Beecher GR, Holden JM, Haytowitz DB, Gebhardt SE, Prior RL. Lipophilic and hydrophilic antioxidant capacities of common foods in the United States. J Agric Food Chem. 2004 Jun 16;52(12):4026-37. PMID: 15186133
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=991) Pomegranate 350+ from Natures Life
Date:
November 18, 2005 09:56 AM
Pomegranate 350mgIntended to provide nutritive support for healthy vascular functions, Pomegranate is a potent antioxidant containing 140mg's of ellagic acid in each capsule.
Pomegranate Definition: The fruit of this tree, having a tough reddish rind, and containing many seeds, each enclosed in a juicy, mildly acidic, red pulp. shrub or small tree native to southwestern Asia having large red many-seeded fruit. large globular fruit having many seeds with juicy red pulp in a tough brownish-red rind.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=946) Nature's Cancer fighters ...
Date:
July 07, 2005 12:36 PM
Cancer has always been a word no one wants to hear from a doctor's lips. But as a fatal disease, cancer has gone from dread to worse, passing heart disease as the number-one killer of Americans under the age of 85 (a category that includes the overwhelming majority of us). While death rates for both illnesses has dropped over the past few years, the improvement has been much more pronounced for cardiovascular disorders. According to the American Cancer Society, 476,009 people died of cancer in 2002 (the last year for which statistics are available). Behind every one of those numbers is a web of lives tangled by cancer's relentless onslaught: A child who misses a mother's comforting arms, a bride without a father to walk her down the aisle, a spouse coming home to a dark, cold house every night. And for those fortunate enough to survive a cancer encounter, there's always the dark worry of recurrence that surfaces with every ache or twinge. Many people think of cancer as either a random calamity of a genetically driven inevitability, but it ain't necessarily so. Diet is coming up big as a major cancer-risk player: For example, eating a lot of red meat, especially highly processed meats such as bacon, has been linked to high colorectal cancer risk in an investigation published by the Journal of the American Medical Association. On the positive side, a number of nutrients have shown cancer-fighting power, such as the recently discovered link between the B vitamin folate and reduced risk of colon and other cancers (see page 57). Other useful nutrients appear on the chart that follows. Of course, risk always varies from person to person, and there are some lifestyle issues, like not smoking, that are no-brainers when it comes to cancer deterrence. But isn't it nice to know that protection from such a terrible disease might be as close as the end of your fork?
Nature's Cancer fightersBerries
Citrus Bioflavonoids
Curcumin
EPA
Green Tea
Lycopene
Mushroom Polysaccarides
Selenium
Soy
Vitamin C
Vitamin D
Vitamin E, Natural
Glossary
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=558) ENDNOTES
Date:
June 23, 2005 11:50 AM
ENDNOTES
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=410) Ellagic Active - Raspberry Extract - Promotes Healthy Cells ... 
Date:
June 01, 2005 01:22 PM
You may think raspberries are strictly a summertime indulgence. Yet scientists know this simple fruit is far more valuable than a delicious snack or gourmet dessert. Raspberries have the highest content of ellagitannins— amazing health compounds— which are converted into ellagic acids in the body. These compounds are highly regarded for their positive effects on the growth and regulation of various cells and tissues, including those in the breast, pancreas, esophageal, skin, colon and prostate. ellagic acid is also a powerful antioxidant (even stronger than vitamin C) that supports DNA integrity and promotes overall cell health, according to animal and in-vitro research. Source Naturals offers ellagic acid in response to a breakthrough in cell research. We strive to be ahead of mainstream nutritional science and are passionate about our commitment to informed health choices. Protective Benefits Dieticians have long stressed the importance of the consumption of fruits and vegetables for general health and well-being, but now these food items are being recognized as even greater contributors to human health. We know that ellagic acid binds to DNA, and acts as a shield, protecting DNA and increasing the expression of the enzyme p21, which arrests division of cells with DNA damage. Raspberries contain phytochemicals that provide protective action: One study showed that ellagic acid was able to induce the production of NAD(P)H:quinone reductase (QR), a major detoxification enzyme. Ellagic acid acts as a free radical scavenger to “bind” irritant-causing chemicals, making them inactive. ellagic acid stimulates the activity of the enzyme glutathione-S-transferase that supports healthy cell growth. Extensive Research Raspberry is also a traditional remedy in support of the gastrointestinal and respiratory tract. It is used to promote healthy blood vessels, as a mouth and throat remedy and is said to help maintain a “normal, balanced feeling” in the stomach. Research studies on the protective effects of ellagic acid have been extensive—there are approximately 126 published studies. Berries also contain a natural form of salicylates, which provide cardio support. British researchers analyzed the blood of subjects and found salicylates were present from dietary sources, including raspberries and blackberries. Researchers at the National Center for Health Statistics (NCHS) in Hyattsville, Maryland established a connection between reduced health risks and increased intake of salicylates. Animal tests also suggest that red raspberry may reduce levels of glucose (blood sugar) to support normal blood sugar levels. Potent Defense Research in the past decade has determined that ellagic acid is one of the most exciting and promising compounds for its striking effect on cell division, regeneration and growth. While ellagic acid has been found to occur naturally in 46 different foods, red raspberry has been identified as having the highest natural content. Each tablet contains 300 mg of raspberry leaf extract (40% ellagitannins), which is ten times higher than other raspberry products. Source Naturals again joins forces with your natural foods retailer to bring you this unparalleled supplement.
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